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Australian Shepherd Lovers Newsletter -- Fatal Drug Reactions and How To Keep Your Aussie Safe
August 10, 2013

You are receiving this because you subscribed to the Australian Shepherd Lovers Newsletter. This newsletter is also available online here. Newsletter #058

Hi Everyone,

I want to make sure you are all aware of a genetic mutation to the MDR1 gene that affects Australian Shepherds. Your Aussie may or may not have it. The only way to know is to have a test done for it. You need to know that this condition can result in fatalities. Dogs with the mutation become highly sensitive to many drugs—drugs used for different things. For example, Ivermectin used for anti-parasite medications or Metronidazole (Flagyl) and Loperamide (Imodium) for diarrhea. Milbemycin (Trifexis) used for heartworm has also been documented to cause problems in dogs with the MDR1 mutation. Other drugs from tranquilizers to chemotherapy agents and cardiac drugs are also implicated.

There are many other drugs that can be dangerous. The only way to know if your dog is at risk is to have them tested for the MDR1 gene mutation. See links below for where you can get the test (these are not advertising links).

Please note that when researching the web many have asked in forums (including the forums on our site) if a given drug is okay for Australian Shepherds. Just because someone else's dog tolerated a drug does NOT mean it is safe for your dog. Their dog may not have the mutation or may be less sensitive to a given drug. The same drug at the same dosage could result in a severe or fatal reaction in another dog.

I would suggest having your dog tested and making sure your vet is aware of the problem and how serious the consequences can be.

MDR1 Testing

North America:
Washington State University

United Kingdom:

Genetic Counselling Services

Genetic Technologies Ltd.
Gribbles Veterinary Pathology

All the Best,

~ Anton


In This Issue:

- Deal Alerts

- Reader's Aussies

- Aussie Art

- Photo of the Month

- Rescue Listings

- Dog Quote for Today

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Deal Alerts

• Our Very Own.... Guide To Australian Shepherd Training & Care Ebook
As a newsletter subscriber you get the ebook for only $9.95 (reg. $17) -- Enter Discount Code NEWS1 (after you click "Add to Cart")
Check out the Ebook here...

Reader's Aussies: Create a Page All About Your Aussie

Some terrific new pages from readers this month...

Australian Shepherds Are The Smartest Dogs Ever

My Aussie Trio

A New Friend

Our Pretty Puppy, Jessie - Almost A Year Old!

Our Girls!

How cool is your Aussie? Why not tell us all about them?! Create a page all about your Aussie and include up to 4 photos! >> Reader's Aussies

Aussie Art

New submissions from readers to our Aussie Art section...

Sparkle - Terrific drawing by a 14 year old reader named Angel. Thanks Angel!

Do you have a piece of Aussome Aussie Art? Post it here—we'd love to see it! >> Aussie Art

Photo of the Month

I've gotten behind on the newsletter so there are two Photos of the Month that I haven't posted here yet. Last month it was the photo of the very athletic Aussie, Jasper, sent in by Todd Wynia. And this month it is twice the fun with Cooper and Bailey showing us how agility is done! Thanks to Mark Brownton for sending in this great photo.

>> Australian Shepherd Photo of the Month and Previous Winners

Rescue Listings

Are you considering getting an Aussie? Why not get an rescue Aussie in need of a loving home like yours?

>> Rescue Listings Page

>> Aussie Rescue Organizations

Dog Quote for Today

"Puppies are nature's remedy for feeling unloved, plus numerous other ailments of life."

~ Richard Allan Palm

Australian Shepherd Breeders

Calling All Breeders—If you are an Australian Shepherd breeder please make sure your listing is up to date. I have made many improvements to the Premium Listings (and dramatically reduced the annual subscription). Whether you opt for that or want to continue with a f'ree listing I still need to hear from you. You can find out more at the following link or email me if you have any questions.

>> Breeders Directory

Did You Get Your Copy of The Aussie Ebook Yet?

Newsletter Subscribers Discount... enter NEWS1 in the "discount code" field (after you click "Add To Cart") and get a special Newsletter Subscriber Discount (get the ebook for only $9.95 instead of the regular $17.00)

• Over 220 photos submitted by our Aussie Community

• Tons of info on training and caring for your Aussie

• Convenient PDF format for instant download

Visit this link to find out more about everything that's included...

Ultimate Guide To Australian Shepherd Training & Care
Note: This is an Ebook in PDF format that you download (no shipping fees or waiting). Book cover shown for illustrative purposes only.

>> Get Your Copy Here...

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Until Next Time...

Check back with us often as we are always adding more great information. Please let us know if there is something you would like to see on

We love to hear from fellow Australian Shepherd Lovers like you. Send us your ideas, your feedback and photos/stories of your Aussie so we can include them on the site.

All the Best and Woof!

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