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My Australian Shepherd, Duke. I forced myself to let my 'pally' go after almost 12 years together. Duke was my a pet of a lifetime and I'll always feel like the luckiest person to have him.
Duke suffered from epilepsy for the last 3 years, the disease progressed to 14 pills a day, well over 100 seizures, but he always came back to me. After a severe cluster episode, I had to end his suffering. Perhaps I should have done it sooner - I think Duke helped with that decision in the end.
We were a pair, I will always miss him.
Epileptic seizures are terrible. The medication and the seizure(s) slowly takes away (as in Duke's case) the dog's quality of life and there is no cure.
Enjoy your friend as long as you can - that's all you can do, that's what I did until I let him go.